These characters in RED, 什么, pinyin: shénme can be used in several ways, here are the six various ways:

[1] (interrogative subject，object，object of prep)

[2] (in indirect questions/speech subject，object) 什么
shénme

[3] (relative) 所…的 suǒ....de

[4] (interrogative，in indirect questions/speech) 什么 shénme

[5] (in exclamations) 多么 duō me

[6] (disbelieving) 什么
shénme

The tone matters.

An exclamation. Or it can be in disbelief. Each said in a different tone gives it a different meaning...